One Two
Sie sind hier: Startseite Research Group Krohne

Retinal Cell Biology Group (T. Krohne)





Research areas

Pathogenesis of age-related macular degeneration (AMD)

  • Innate immunity in AMD: NLRP3 inflammasome activation induced by lipofuscin phototoxicity in age-related macular degeneration (AMD) 

Stem cells in retinal diseases

  • In vitro modelling of retinal neurodegenerative diseases using patient-derived induced pluripotent stem cells (iPS cells) 

Ocular Pharmacokinetics

  • Pharmacokinetics of VEGF-inhibitory drugs following intravitreal injection
  • Pharmacokinetics of intravitreal bevacizumab
    Quantification of bevacizumab concentration in human aqueous following intravitreal injection
    (Liu, Strack, Meyer, Krohne)